Long QT Syndrome Panel
- Long QT syndrome (LQTS) is a disorder of the heart’s electrical activity that can cause sudden, uncontrollable, and dangerous arrhythmias in response to exercise or stress (1). These changes in the heart beat can trigger sudden fainting or seizures and even death (2). The syndrome is usually diagnosed after a person has a cardiac event, and a history of cardiac events is the most typical clinical presentation in patients with LQTS (3). Treatments for LQTS include surgery, implantable devices, and certain medications to prevent a chaotic heart rhythm. Many individuals are born with a genetic mutation that puts them at risk for LQTS (2). About 80% of people who definitely have LQTS have a positive genetic test result, indicating that genetic mutations in certain genes have a large correlation with the syndrome. Genetic testing for LQTS is available and can generally find the genetic cause of about 75% of the cases.
- Genes (20): ABCC9, ACTC1, ACTN2, AKAP9, ANK2, CACNA1C, CACNB2, CALM1, CALM3, CAV3, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNQ1, SCN4B, SCN5A, and SNTA1
Test Code: 3031
• Molecular confirmation of a clinical diagnosis of Long QT Syndrome in symptomatic patients.
• Carrier testing in asymptomatic family members of an affected proband.
Test Info Sheet: Long QT Syndrome Panel
Requisition: Cardiac Test Requisition Form
- Turn-Around Time: 4 Weeks
Preferred Specimen: 3-5 mL Whole Blood – Lavender Top Tube
Other Specimens: See details here
- CPT Codes: 81403×1, 81404×1, 81405×1, 81406×3, 81407×1, 81479×13
Pricing: Please contact us at (949) 916-8886 or firstname.lastname@example.org
- Methodology: Next-Generation Sequencing (NGS)
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